Brochure

Through the Eye of Discovery

2026 Brochure - Published November 13, 2025

Dear Colleagues,

The Coalition for Academic Scientific Computation (CASC) is proud to represent a community of professionals who are building the foundation for America’s competitiveness in science, technology, and innovation. Our members provide the advanced cyberinfrastructure-high-performance computing, data management, and expertise-that enables America’s greatest minds to tackle questions that matter for our future: from accelerating drug discovery, to advancing artificial intelligence (Al), to enabling more resilient supply chains. The stakes have never been higher. Other nations, particularly China, are investing aggressively in research and technology with the clear intent to lead in areas like Al, advanced materials, robotics, and manufacturing. If the U.S. does not accelerate its investment in computational science and the workforce that supports it, we risk not only losing ground in global competitiveness but also a brain drain of our most talented scientists and engineers. Our loss would be their gain.

At CASC, we see every day the impact of computational science on American innovation. Our members serve as both the technical backbone and the intellectual drivers of progress in the fields that will fuel the future. We play a critical role in preparing the next generation of the Al workforce-students who will graduate with the skills needed to drive discovery, grow businesses, and strengthen our economy. This brochure highlights CASC’s role in amplifying those efforts. You will see examples of:

  • Public-private partnerships that spur solutions and ensure discoveries move into practice.
  • The research ecosystem as a workforce engine, providing the next generation with the experience they need to lead critical industries of the future economy.
  • The payoff of investment in computation for national competitiveness, job creation, and a new future for U.S. manufacturing.

CASC members proudly serve our country by sustaining our nation’s edge in science, technology, and workforce development. Our efforts not only maintain critical infrastructure but also shape the collaborative culture and expertise that make America’s researchers the best in the world. The work we do today ensures that the U.S. remains at the forefront of global discovery, innovation, and economic vitality. As you read through this brochure, I hope you will take away the urgency-and the opportunity-of continued investment in computational science. By strengthening our nation’s commitment to cyberinfrastructure, research computing, and the workforce that supports them, we safeguard America’s leadership in discovery and innovation.

Sincerely,
Richard Knepper
Chair, Coalition for Academic Scientific Computation

Cover Image: Mallorie McIlwain, Penn State Institute for Computational and Data Sciences (ICDS)

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